Sensing with FETs - once, now and future
نویسندگان
چکیده
In this paper a short overview is given of the several FET-based sensor devices and the operational principle of the ISFET is summarized. Some of the shortcomings of the FET sensors were circumvented by an alternative operational mode, resulting in a device capable of acid/base concentration determination by coulometric titrant generation as well as in an original pH-static enzyme sensor. A more recent example is presented in which the ISFET is used for the on-line monitoring of fermentation processes. Future research is directed towards direct covalent coupling of organic monolayers on the silicon itself. In addition, the fieldeffect can be applied to the so-called semiconducting nanowire devices, ultimately making single molecule detection of charged species possible.
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